Hydroxyzine and dayquil

Hydroxyzine (Oral) Brand Names: Atarax, Rezine, Vistaril. Hydroxyzine reduces activity in the central nervous system. It also acts as an antihistamine that reduces the effects of natural chemical ...

difficulty with swallowing. dizziness. fainting. fast heartbeat. hives, itching, or skin rash. irregular or slow heart rate. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. trouble breathing. unusual tiredness or weakness.Make sure your doctor knows if you are pregnant. Do not use this medicine during the early part of a pregnancy unless your doctor tells you to. This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you. This medicine will add to the effects of alcohol and other ...Hydroxyzine, an antihistamine medication, exerts its effects by targeting histamine receptors in the brain. Histamine is a neurotransmitter associated with alertness and wakefulness, and by blocking the histamine receptors, hydroxyzine effectively dampens the activity of histamine, leading to a calming effect.Vistaril (hydroxyzine pamoate) and Atarax (hydroxyzine hydrochloride) are antihistamines with anticholinergic (drying) and sedative properties used as sedatives to treat anxiety and tension.. Vistaril is also used together with other medications given for anesthesia.Vistaril may also be used to control nausea and vomiting, or to treat allergic skin reactions such …Got a pressing headache? How about an aching sunburn? Prevention magazine asked seven experts for their home remedies to cure common health concerns. For example, if your teeth are...Oral. Symptomatic relief of anxiety: 50–100 mg qid. Management of pruritus: 25 mg tid–qid. Sedative (preoperative and postoperative): 50–100 mg. IM. Psychiatric and emotional emergencies, including alcoholism: 50–100 mg immediately and q 4–6 hr as needed. Nausea and vomiting: 25–100 mg. Preoperative and postoperative, prepartum and ...Dec 12, 2022 · Atarax; NOVO-Hydroxyzin; PMS-HydrOXYzine HCl [DSC] What is this drug used for? It is used to treat itching. It is used to treat anxiety. It is used to put your child to sleep for surgery. It is used to treat mood problems. It is used to treat upset stomach and throwing up. It may be given to your child for other reasons. Talk with the doctor.

Typical dosing for Hydroxyzine (Vistaril) Itching. Adults: The typical dose is 25 mg by mouth three to four times daily. Children over 6 years old: The typical dose is 50 to 100 mg by mouth daily, given in separate doses throughout the day. Children under 6 years old: The typical dose is 50 mg by mouth daily, given in separate doses throughout ...4 days ago · Descriptions. Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). Hydroxyzine. Kelley K. Kiningham, in xPharm: The Comprehensive Pharmacology Reference, 2007 Hydroxyzine, a piperazine derivative, is a competitive antagonist of histamine H 1-receptors.Hydroxyzine has antiemetic and sedative effects that are thought to be mediated by its actions in brain. Hydroxyzine is used for the management of …For oral dosage forms (suspension and tablets): For seizures: For patients taking oxcarbazepine together with other medicines: Adults and children 17 years of age and older—At first, 300 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 1200 mg per day. Heart failure (HF) remains the leading discharge diagnosis among patients ≥65 years of age. The estimated cost for treatment of HF in Medicare recipients is $31 billion and is expected to increase to $53 billion by 2030. 1 Hospitalization for HF is the largest segment of those costs. Matador is a travel and lifestyle brand redefining travel media with cutting edge adventure stories, photojournalism, and social commentary. Like other character parks, Sanrio Puro...Official answer. by Drugs.com. Hydroxyzine is intended for short-term use only (less than 4 months) when used to treat anxiety. Using hydroxyzine long-term would be considered an off-label use for the drug because there are no studies looking at the long-term effects of hydroxyzine. Some research suggests a link between long-term use of ...

Hydroxyzine is a first-generation histamine H 1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.Fever. “For fever, the two things we use more often than anything are acetaminophen and ibuprofen ,” Vyas said. Tylenol is a common brand of acetaminophen; Advil and Motrin are common brands of ibuprofen. As with anything, it’s important to check with a primary care provider on what you should and shouldn’t be taking—for the …Hydroxyzine - What is it for. Hydroxyzine can be used to relieve symptoms such as: Itch. Anxiety/tension. It may be used for short term treatment of insomnia (sleep problems) as well. It may be given to you for other reasons. Do check with your doctor what you are taking this for.Nyquil and Dayquil contain 37 and 15 mg/30 mL, respectively, of sodium. 314,315 Gaviscon has 52 mg of sodium per 15 mL, which, if the recommended 30-mL dose is taken 4 times daily, equates to >400 mg of sodium per day. 316Almost 30 million adults in the U.S. are living with schizophrenia, bipolar disorder, or depression.Treatment for these conditions may include a medication called quetiapine (Seroquel, Seroquel XR).. Quetiapine is an atypical antipsychotic.It comes as both an immediate-release (IR) and extended-release tablet.Both forms are FDA …

Movie showtimes livonia amc 20.

Almost 30 million adults in the U.S. are living with schizophrenia, bipolar disorder, or depression.Treatment for these conditions may include a medication called quetiapine (Seroquel, Seroquel XR).. Quetiapine is an atypical antipsychotic.It comes as both an immediate-release (IR) and extended-release tablet.Both forms are FDA …According to Vicks.com, the correct dose of DayQuil Cold and Flu liquid is 2 tablespoons, or 30 milliliters, every four hours for adults and children 12 years or older. Children fr...Hydroxyzine (hye drox' i zeen) is a first generation antihistamine that is used mostly to treat itching and nausea. Because of its sedating effects, hydroxyzine is also used for anxiety, tension and as a mild sleeping aid. Hydroxyzine belongs to the piperazine class of antihistamines (with cyclizine and meclizine) which are more commonly used ... Hydroxyzine is used to treat itching caused by allergies. It is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Hydroxyzine may also be used short-term to treat anxiety or to help you feel sleepy/relaxed before and after surgery. Thank you for waiting.I am very sorry for your symptoms.I understand your concern.The combination can cause side effects like increased drowsiness & a bit dizziness.Those combination can reduce mental alertness.If you take Nyquil, please avoid alcohol.You should avoid driving now too.I hope this information will be helpful.If you have any query ...

In adults: Following concerns of heart rhythm abnormalities, the safety and efficacy of hydroxyzine has been reviewed by the European Medicines Agency. The review concludes that hydroxyzine is associated with a small risk of QT-interval prolongation and torsade de pointes; these events are most likely to occur in patients who have risk factors ... Hydroxyzine hydrochloride is designated chemically as (±)-2-[2-[4-( p-Chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol dihydrochloride.Its structural formula is as follows: Inactive Ingredients for Hydroxyzine Hydrochloride Oral Solution, USP (Syrup) are: alcohol 0.5% (v/v); sucrose; methylparaben; peppermint flavor; propylene glycol; …Can you take Hydroxyzine and Dayquil together? Nope. You're taking two different pain relievers in the Motrin and the DayQuil and two different allergy medicines in Zyrtec and DayQuil. If you have ...Hydroxyzine is a medication that treats the symptoms of allergies and allergic reactions. It may also be used to treat anxiety. It works by blocking histamine, a substance released by the body during an allergic reaction. It’s a type of antihistamine. It may cause drowsiness.Results: The in vivo outcomes (elevated plus maze, light/dark transition, and marble burying tests) of hydroxyzine monotherapy-treated group showed a significant anxiolytic activity. The combination-treated group was found to be better than control and aripiprazole-treated groups. The combination-treated group showed a significant increase in the level of …restless muscle movements in your eyes, tongue, jaw, or neck; tremor (uncontrolled shaking); confusion; or. seizure (convulsions). Less serious Atarax side effects may include: dizziness, drowsiness; blurred vision, dry mouth; or. headache. This is not a complete list of side effects and others may occur.Feb 12, 2024 · Hydroxyzine pamoate is a light yellow odorless powder, practically insoluble in water and methanol and freely soluble in dimethylformamide. It is chemically designated as (±)-2- [2- [4- (p-Chloro-α-phenylbenzyl)-1- piperazinyl]ethoxy]ethanol 4,4 -methylenebis [3-hydroxy-2-naphthoate] (1:1) and can be structurally represented as follows ... Official answer. by Drugs.com. Hydroxyzine is intended for short-term use only (less than 4 months) when used to treat anxiety. Using hydroxyzine long-term would be considered an off-label use for the drug because there are no studies looking at the long-term effects of hydroxyzine. Some research suggests a link between long-term use of ...Mar 8, 2024 · The bottom line. Hydroxyzine (Vistaril) is a prescription medication that treats conditions such as anxiety, itching, and chronic hives in children and adults. It’s available as capsules, tablets, and an oral syrup.Your hydroxyzine dosage can depend on your age, medical conditions, and why you’re taking it. Most adults take between 25 mg ... Customer Care direct line. 0333 2005 345. Paramol Tablets - Summary of Product Characteristics (SmPC) by Reckitt Benckiser Healthcare (UK) Ltd.

Side Effects. Drug information provided by: Merative, Micromedex® Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Uses. This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis …Hydroxyzine works by limiting the effects of histamine, thereby reducing the prevalence of allergic reactions such as rash and itchiness . It also acts as a sedative, by impacting activity in certain parts of the central nervous system, so it can be used as an effective treatment for anxiety and sleep disturbances [4] [5] .Atarax; NOVO-Hydroxyzin; PMS-HydrOXYzine HCl [DSC] What is this drug used for? It is used to treat itching. It is used to treat anxiety. It is used to put you to sleep for surgery. It is used to treat mood problems. It is used to treat upset stomach and throwing up. It may be given to you for other reasons. Talk with the doctor.Avoid taking medications you don't necessarily need, such as herbal medications, high-dose vitamins and unusual supplements. Also ask about the timing. For example, taking medication immediately after breastfeeding might help lower your baby's exposure. However, different drugs peak in breast milk at different times.severe dizziness, fainting; or. a seizure (convulsions). Side effects such as drowsiness and confusion may be more likely in older adults. Common Vistaril side effects may include: drowsiness; headache; dry mouth; or. skin rash. This is not a complete list of side effects and others may occur.Hydroxyzine (Vistaril) is an antihistamine prescribed for allergies, itching, and anxiety. It interacts with various other medications and substances. Opioids, …Yes, Hydroxyzine does expire. Everything in this drug from the active chemical ingredient to preservatives has an expiry date and they may begin to lose their effectiveness once that date has passed. Therefore, the use of expired Hydroxyzine is not recommended. Although some medications can remain effective for an extended …Vistaril (hydroxyzine pamoate) and Atarax (hydroxyzine hydrochloride) are antihistamines with anticholinergic (drying) and sedative properties used as sedatives to treat anxiety and tension.. Vistaril is also used together with other medications given for anesthesia.Vistaril may also be used to control nausea and vomiting, or to treat allergic skin reactions such …Hydroxyzine, also known by its brand name Vistaril, is an antihistamine that works by blocking the effects of histamine in the body. It is commonly prescribed to treat itching, anxiety, and allergic reactions. Hydroxyzine is available in both oral and injectable forms, providing flexibility in administration depending on the severity of symptoms.

Joe fonzi age.

Longs ewa beach pharmacy.

Available as hydroxyzine pamoate and hydroxyzine hydrochloride; dosage expressed in terms of the hydrochloride. Use the smallest possible effective dosage. Pediatric Patients Anxiety Oral. Children <6 years of age: 50 mg daily given in divided doses. Children ≥6 years of age: 50–100 mg daily given in divided doses. Pruritus OralHydroxyzine vs Xanax: Comparison and Side Effects As the most common mental health condition, anxiety impacts more than 30 percent of American adults at least some time in their lives. While many manage their anxiety through treatments such as therapy and lifestyle changes, for many others, medication is an effective way to address …Three of the drugs — hydroxyzine, diphenhydramine and azelastine — showed direct, statistically significant antiviral effects on the SARS-CoV-2 virus. Hydroxyzine, sold as Atarax, and the nasal spray …Coping strategies play a crucial role in managing withdrawal symptoms and supporting overall well-being. Cognitive-behavioral therapy (CBT) and support groups can be beneficial for individuals dealing with hydroxyzine withdrawal. CBT helps individuals identify and change negative thought patterns and develop healthier coping mechanisms.Typical dosing for Hydroxyzine (Vistaril) Itching. Adults: The typical dose is 25 mg by mouth three to four times daily. Children over 6 years old: The typical dose is 50 to 100 mg by mouth daily, given in separate doses throughout the day. Children under 6 years old: The typical dose is 50 mg by mouth daily, given in separate doses throughout ...Hydroxyzine. Hydroxyzine is a first-generation antihistamine (and anticholingeric) with a variety of uses and indications, including uses as an anxiolytic. Hydroxyzine's predominant mechanism of action is as a potent and selective histamine (H1) receptor inverse agonist. This action is responsible for its antihistamine and sedative …Last updated on May 23, 2022. Uses. Warnings. Before taking. Dosage. Side effects. Interactions. FAQ. What is hydroxyzine? Hydroxyzine is an antihistamine that reduces …Side Effects. Drowsiness, dizziness, blurred vision, constipation, or dry mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To relieve dry mouth ... ….

Oct 16, 2023 · Hydroxyzine Oral Solution Description. Hydroxyzine hydrochloride is designated chemically as (±)-2- [2- [4- ( p -Chloro-α-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol dihydrochloride. Inert ingredients: citric acid, peppermint flavor, sodium benzoate, sucrose and water. Citric acid and/or sodium citrate may be used to adjust the pH when necessary. Just got prescribed hydroxyzine to take for 14 days for my late night panic attacks. Last night i had a really bad one where it’s caused me to feel numbness within my face and tongue etc. So i went to a local clinic , just a few hours ago they prescribed me hydroxyzine to help with the late night anxiety attacks i may have throughout the night. Uses. Hydroxyzine is used to treat itching caused by allergies. It is an antihistamine and works by blocking a certain natural substance ( histamine) that your body makes during an allergic ... severe dizziness, fainting; or. a seizure (convulsions). Side effects such as drowsiness and confusion may be more likely in older adults. Common Vistaril side effects may include: drowsiness; headache; dry mouth; or. skin rash. This is not a complete list of side effects and others may occur.restless muscle movements in your eyes, tongue, jaw, or neck; tremor (uncontrolled shaking); confusion; or. seizure (convulsions). Less serious Atarax side effects may include: dizziness, drowsiness; blurred vision, dry mouth; or. headache. This is not a complete list of side effects and others may occur.For controlling anxiety and produce sleep before surgery: Adults—50 to 100 milligrams (mg) per day. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 0.6 milligram (mg) per kilogram (kg) of body weight per day. For oral dosage forms (Vistaril® capsules or suspension):difficulty with swallowing. dizziness. fainting. fast heartbeat. hives, itching, or skin rash. irregular or slow heart rate. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. trouble breathing. unusual tiredness or weakness.How it works. Types. Possible side effects. Possible precautions. Possible interactions. FAQs. Individuals should not take more than 4 doses of DayQuil within 24 hours. Taking more than the...Hydroxyzine Pamoate (Vistaril): Uses, Side Effects, Dosage. Hydroxyzine pamoate (the generic version of Vistaril) is in the class of drugs known as antihistamines. Hydroxyzine has anticholinergic and sedative properties and is often prescribed to treat hives, itching, dermatitis, and allergic skin reactions. The drug works by reducing central ... Hydroxyzine and dayquil, Dosing: Adult. Antiemetic: IM: 25 to 100 mg/dose. Anxiety: Oral: Manufacturer’s labeling: 50 to 100 mg 4 times daily. Alternative recommendations (off-label dosing): 37.5 to 75 mg daily in divided doses (WFSBP [Bandelow 2008]; WFSBP [Bandelow 2012]) IM: Initial: 50 to 100 mg, then every 4 to 6 hours as needed., fatigue. weakness. low blood pressure. headache*. dry mouth *. mild allergic reaction *. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer ..., Rating Action: Moody's upgrades ratings of nine Indonesian financial institutions to Baa2Vollständigen Artikel bei Moodys lesen Vollständigen Artikel bei Moodys lesen Indices Commo..., We have used a combined methodological approach to re‐evaluate the cardiac safety profile of hydroxyzine, including: (1) a full review of the sponsor pharmacovigilance safety database to examine real‐world data on the risk of QT prolongation and/or TdP associated with hydroxyzine use and (2) nonclinical …, Customer Care direct line. 0333 2005 345. Paramol Tablets - Summary of Product Characteristics (SmPC) by Reckitt Benckiser Healthcare (UK) Ltd., As such, their anti-allergy effects are longer lasting. OTC second-generation H1-antihistamines used for the treatment of nasal allergies include: Allegra (fexofenadine) Astepro nasal spray (azelastine) Claritin (loratadine) Zyrtec (cetirizine) Xyzal (levocetirizine) Prescription second-generation H1-antihistamines sometimes used for the ..., Hydroxyzine is also used along with other medications in adults and children as a sedative before and after general anesthesia for surgery. Hydroxyzine is in a class of medications called antihistamines. It works by blocking the action of histamine a substance in the body that causes allergic symptoms. It also works by decreasing activity in ..., Hydroxyzine: Hydroxyzine belongs to the class of medications called antihistamines. It is used to relieve itching and other symptoms caused by allergic conditions. It can help to alleviate itching due to an adverse reaction to opioid medications. It works by blocking the actions of one of the body's natural chemicals known as histamine. Histamine is …, Iterax is a first-generation antihistamine that is used to treat allergies and anxiety. Due to its sedative effects, it is sometimes used to pre-medicate patients prior to surgery...., Meloxicam (Mobic) is a prescription-only nonsteroidal anti-inflammatory drug (NSAID). Several medications and substances interact with it. Meloxicam interacts with blood thinners, some antidepressants, and certain blood pressure medications. Lithium (Lithobid), methotrexate (Trexall), and alcohol also interact with it., Thank you for waiting.I am very sorry for your symptoms.I understand your concern.The combination can cause side effects like increased drowsiness & a bit dizziness.Those combination can reduce mental alertness.If you take Nyquil, please avoid alcohol.You should avoid driving now too.I hope this information will be helpful.If you have any query ..., Drowsiness, dizziness, blurred vision, dry mouth, constipation, or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To relieve dry mouth ..., Does magnesium help you relax and sleep? If so, how much do you have to take and which type of magnesium? Here's all you need to know. Magnesium may help you sleep better by enhanc..., Available as hydroxyzine pamoate and hydroxyzine hydrochloride; dosage expressed in terms of the hydrochloride. Use the smallest possible effective dosage. Pediatric Patients Anxiety Oral. Children <6 years of age: 50 mg daily given in divided doses. Children ≥6 years of age: 50–100 mg daily given in divided doses. Pruritus Oral, The primary outcome criterion was the change in the HAM-A score from baseline to 12 weeks of double-blind treatment with hydroxyzine compared with placebo. Results: In the intent-to-treat analysis, the mean +/- SD change in HAM-A scores from baseline to endpoint was -12.16 +/- 7.74 for hydroxyzine and -9.64 +/- 7.74 for placebo (p =.019 ..., Small occasional doses of hydroxyzine would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause drowsiness and other effects in the …, Involuntary motor activity ( tremor, convulsions) usually with doses considerably higher than those recommended. Clinically significant respiratory depression has not been reported at recommended doses. Postmarketing side effects of hydroxyzine reported include: Allergic reactions. Headache. Hallucinations. Itching. , According to Vicks.com, the correct dose of DayQuil Cold and Flu liquid is 2 tablespoons, or 30 milliliters, every four hours for adults and children 12 years or older. Children fr..., Thank you for waiting.I am very sorry for your symptoms.I understand your concern.The combination can cause side effects like increased drowsiness & a bit dizziness.Those combination can reduce mental alertness.If you take Nyquil, please avoid alcohol.You should avoid driving now too.I hope this information will be helpful.If you have any query ..., Hb (Hemoglobin) Complete Hemogram (CBC & ESR) Atarax 10mg Tablet is used in the treatment of Anxiety,Skin conditions with inflammation & itching. View Atarax 10mg Tablet (strip of 15.0 tablets) uses, composition, side-effects, price, substitutes, drug interactions, precautions, warnings, expert advice and buy online at best price on 1mg.com., HYDROXYZINE (hye DROX i zeen) treats the symptoms of allergies and allergic reactions. It may also be used to treat anxiety or cause drowsiness before a procedure. It works by blocking histamine, a substance released by the body during an allergic reaction. It belongs to a group of medications called antihistamines. , Browse sample topics. Find information on Hydroxyzine (Vistaril) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF., Read this chapter of Davis's Drug Guide for Rehabilitation Professionals online now, exclusively on F.A. Davis PT Collection. F.A. Davis PT Collection is a subscription-based resource from McGraw Hill that features trusted content from the best minds in PT., Mar 8, 2024 · The bottom line. Hydroxyzine (Vistaril) is a prescription medication that treats conditions such as anxiety, itching, and chronic hives in children and adults. It’s available as capsules, tablets, and an oral syrup.Your hydroxyzine dosage can depend on your age, medical conditions, and why you’re taking it. Most adults take between 25 mg ... , Hydroxyzine (Oral) Brand Names: Atarax, Rezine, Vistaril. Hydroxyzine reduces activity in the central nervous system. It also acts as an antihistamine that reduces the effects of natural chemical ... , According to Vicks.com, the correct dose of DayQuil Cold and Flu liquid is 2 tablespoons, or 30 milliliters, every four hours for adults and children 12 years or older. Children fr..., restless muscle movements in your eyes, tongue, jaw, or neck; tremor (uncontrolled shaking); confusion; or. seizure (convulsions). Less serious Atarax side effects may include: dizziness, drowsiness; blurred vision, dry mouth; or. headache. This is not a complete list of side effects and others may occur., The show uses autism as a plot device to reinforce typical narratives about sympathetic nerds and the beleaguered women who date them. The new Netflix sitcom Atypical has been bill..., Hydroxyzine. Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, insomnia, anxiety, and nausea, including that due to motion sickness. [8] It is used either by mouth or injection into a muscle. [8], Hydroxyzine is also used along with other medications in adults and children as a sedative before and after general anesthesia for surgery. Hydroxyzine is in a class of medications called antihistamines. It works by blocking the action of histamine a substance in the body that causes allergic symptoms. It also works by decreasing activity in ..., This includes nosebleeds, unexplained bruising, and bleeding in your urine or gums. If you’re taking warfarin, you may have more frequent blood tests while you’re taking trazodone. This will help your provider decide if your warfarin dose needs to be adjusted. 3. Medications that affect trazodone metabolism., Jul 29, 2021 · Alprazolam is a benzodiazepine and belongs to the same family as lorazepam (Ativan) and clonazepam (Klonopin). This medication is FDA-approved to treat anxiety disorders (including GAD) and panic disorder. As with hydroxyzine, alprazolam is intended for short-term use — up to 4 months for anxiety disorders and up to 10 weeks for panic disorder. , fatigue (low energy) headache*. insomnia (trouble falling and staying asleep) dizziness. dry mouth *. confusion. constipation*. mild allergic reaction *. * To learn more about this side effect ...